Ayesha received her medical training at The Aga Khan University Medical College in Pakistan and specialized in general adult psychiatry during her residency at Duke University Medical Center. She completed a clinical psychopharmacology preceptorship through Duke-Glaxo Wellcome and served as Executive Chief Resident during her time at Duke Medical Center. 

She is a Diplomate of the American Board of Psychiatry & Neurology and a member of the American Psychiatric Association. She is a Clinical Associate in the Department of Psychiatry and Behavioral Sciences at Duke. Her clinical experience is broad based, and she has a special interest in chronic psychiatric illness and cross-cultural issues.